Industries · Immuno-oncology

Immuno-oncology

OMICS4 runs the multi-omics profiling behind your tumor microenvironment studies (bulk and single-cell RNA-seq, immune profiling and biomarker sample workflows) via our in-house platforms.

Platforms used in this field

Overview

Tumor and immune compartments, sequenced

OMICS4 runs the laboratory work behind immuno-oncology studies. Tumor and immune compartments are extracted, sequenced and quality-controlled in our own laboratories, and returned as primary data your team can analyse directly or hand to GenXMap.

Platforms

Platforms that run an IO study

Transcriptomics

Bulk and single-cell RNA sequencing of tumor and immune compartments.

  • Bulk RNA-seq across a cohort
  • Single-cell library preparation and sequencing
  • RT-qPCR confirmation of selected transcripts
Book this platform

Genomics

Whole exome and targeted panel sequencing on tumor material.

  • NGS library preparation
  • Whole exome sequencing
  • Targeted panels for known variants
Book this platform

Quantitative PCR & Genotyping

Orthogonal confirmation of a candidate marker.

  • qPCR across many samples
  • Digital PCR for low-abundance variants
  • Genotyping on known variants
Book this platform

Extraction & Quality Control

RNA and DNA recovered from difficult tumor material.

  • FFPE blocks and slides
  • Fresh-frozen tissue, PBMC, whole blood
  • A QC report on every sample
Book this platform

Samples we accept

FFPE blocks and slides, fresh-frozen tumor tissue, core biopsies, PBMC, whole blood and dissociated cell suspensions. Input amounts, RIN thresholds and DNA quality criteria are published per sample type. Archival and low-input material is handled routinely: if your material sits below the published thresholds, say so in the quote request and we will tell you what is feasible before you ship.

Multi-site collections, one batch

Biopsies for an IO cohort rarely come from one place. Collections arriving from several clinical sites are registered on reception and consolidated into one batch, processed under a single documented protocol, so that a difference between sites does not become a difference between runs.

What you receive

A QC report for every sample. Sequencing files and, where the service covers it, aligned and quantified outputs. Result tables for PCR and protein work. Exports in the formats your team already imports, and turnaround published per service.

Where the bench stops

Analysis, integration, biomarker discovery and modelling are not part of a platform booking. They are run by GenXMap’s computational team. Ask for them in the quote request and both are scoped together.

Analysis at GenXMap

Have a project in this space?

Tell us the sample type, the number of samples and the timeline.

Book a service